Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment

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Constitutive expression and roles of interleukin-8 in canine hemangiosarcoma

Results IL-8 mRNA expression was variable among the tissue samples and both IL-8 mRNA and protein were variable among the cell lines. In contrast, IL-8 receptor mRNA and protein showed minimal variance. “IL-8 high” and “IL-8 low” groups were defined from the HSA tumor samples based on gene expression profiles. The “IL-8 high” group was associated with a “reactive microenvironment,” showing enri...

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ژورنال

عنوان ژورنال: Experimental Cell Research

سال: 2014

ISSN: 0014-4827

DOI: 10.1016/j.yexcr.2014.02.020